M
Minoxidil
FDA-approvedTopical
Topical solution or foam. The longest-established hair-loss therapy.
Evidence
Strong randomised trial evidence for androgenetic alopecia in both men and women. Effects plateau around 12 months and reverse if stopped.
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01
Aesthetics
Hair and skin. Almost everything here works better the earlier you start, and most of it stops working when you stop.
Mo
Minoxidil, oral
Off-labelOral
Low-dose oral, when topical irritates the scalp or stops working.
Evidence
Growing observational and small-trial evidence at low doses. Systemic, so it needs a cardiovascular history first — this is not topical with a different delivery.
F
Finasteride
FDA-approvedOral
5-alpha reductase inhibitor. Blocks conversion of testosterone to DHT.
Evidence
Strong trial evidence for slowing and partially reversing male pattern loss. Sexual side effects are real, reported in a minority, and require an honest conversation before starting.
D
Dutasteride
Off-labelOral
More complete DHT suppression than finasteride.
Evidence
Head-to-head data shows greater DHT suppression and greater hair count than finasteride. Approved for prostate enlargement, not hair — longer half-life, so side effects take longer to clear.
Ks
Ketoconazole shampoo
FDA-approvedTopical
Antifungal with a mild anti-androgenic effect at the scalp.
Evidence
Modest supporting evidence as an adjunct. Not a primary therapy, but it stacks cleanly and carries almost no downside.
P
PTD-DBM
Not offeredResearch only—
A Wnt-pathway peptide that circulates in looksmaxxing communities.
Evidence
Studied in animal hair-regeneration models. No human trials establishing safety or dosing. Listed here because people ask about it, and because the honest answer is that nobody knows.
T
Tretinoin
FDA-approvedTopical
Topical retinoid. The most established agent in skin treatment.
Evidence
The best-evidenced topical in dermatology. Decades of trial data for photoaging, texture, and acne. The first eight weeks are usually worse before better, which is why most people quit too early.
Aa
Azelaic acid
FDA-approvedTopical
For redness, post-inflammatory marks, and inflammatory acne.
Evidence
Good trial evidence for rosacea and acne. Better tolerated than tretinoin, and safe in pregnancy, which matters for some patients.
G
GHK-Cu
Not offeredCosmetic / OTCTopical
Copper tripeptide, sold as a cosmetic ingredient.
Evidence
Evidence is largely in-vitro and manufacturer-funded. Sold as a cosmetic ingredient, not a drug. Not offered — but if you're using it, that is worth telling your physician.
How to read the tags
- FDA-approved
- Approved by the FDA for this use.
- Off-label
- An approved drug used outside its labeled indication — ordinary, legal medicine at a physician's discretion.
- Compounded
- Prepared by a compounding pharmacy. Not FDA-approved as a finished product.
- Cosmetic / OTC
- Sold as a cosmetic or over-the-counter ingredient, not a prescription drug.
- Research only
- Investigational. No established basis for human prescribing. Listed for transparency; not offered.
Other pillars